By Tapan K Basu, N Temple, Manohar L. Garg

ISBN-10: 0851993346

ISBN-13: 9780851993348

Antioxidants play an incredible function within the development of significant human degenerative illnesses and prerequisites. This ebook covers antioxidants and their mechanisms of motion; their function in a complete array of stipulations together with heart affliction, malignant disorder, diabetes, cataracts, respiration sickness, cystic fibrosis, cognitive services, and getting older; their symptoms for oxidative tension; and buyer concerns. nearly all of chapters were constructed from papers awarded on the sixth global Congress in scientific food, held in Banff, Canada, July 1997.

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Extra resources for Antioxidants in Human Health and Disease

Sample text

D. (1997) Endogenous antioxidants: role of antioxidant enzymes in biological system. In: Shaihids, F. ) Natural Antioxidants: Chemistry, Health Effects and Applications. AOCS Press, Champaign, Illinois, pp. 258–270. 03 Antioxidants 24/5/99 11:06 am Page 27 Immunological Role of Antioxidant Vitamins ADRIANNE BENDICH 3 New Product Research, SmithKline Beecham Consumer Healthcare, Parsippany, New Jersey, USA Introduction Free radicals, which are highly reactive molecules with one or more unpaired electrons, can cause damage to cell structures and consequently may adversely affect immune functions (Machlin and Bendich, 1987; Halliwell, 1995; Bendich, 1996).

Since these dietary antioxidants are exogenous in nature, their levels can be manipulated by supplements and dietary modifications. There also appear to be a variety of synthetic compounds such as probucol and butylated hydroxytoluene (BHT), with an antioxidant activity. The use of these compounds, however, is limited by their possible unwanted side-effects (Thompson and Moldeus, 1988). The potential of dietary antioxidants to reduce the risk of coronary vascular disease (CVD), is gaining a great deal of interest in the medical and scientific communities.

V. (1992) Safety aspects of food preservatives. Food Additives and Contaminants 9, 562–577. V. and Sapota, A. (1996) Chemical toxicity and reactive oxygen species. International Journal of Occupational Medicine and Environmental Health 9, 331–340. A. and Appel, P. (1981) Quinone stimulated superoxide formation by subcellular fractions, isolated hepatocytes and other cells. Molecular Pharmacology 20, 387–394. J. V. (1989) Effects of acute and sub-chronic administration of iron nitrilotriacetate in the rat.

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Antioxidants in Human Health and Disease by Tapan K Basu, N Temple, Manohar L. Garg

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