By Chandan K. Sen, Lester Packer, Patrick A. Baeuerle
This quantity addresses oxidant-reduction or redox and antioxidant delicate molecular mechanisms and the way they're implicated in several disorder procedures. attainable suggestions to pharmacologically and/or nutritionally manage such redox-sensitive molecular responses are emphasised. Key Features:* Reactive species as intracellular messengers* Redox legislation of mobile responses* medical implications of redox signaling and antioxidant treatment
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Additional resources for Antioxidant and Redox Regulation of Genes
Pp. 279-309. Academic Press, New York. , and Sugden, P. H. (1997). Mitogen-activated protein kinases are activated by oxidative stress and cytokines in neonatal rat ventricular myocytes. Biochem. Soc. Transac. 25, $566. , and van de Vorst, A. (1987). Singlet oxygen-induced mutations in M13 lacZ phage DNA. EMBO J. 6, 3155-3161. , and Davis, R. J. (1994). JNKI: A protein kinase stimulated by UV light and ha-ras that binds and phosphorylates the c-Jun activation domain. ) 76, 1025-1037. , DiDonato, J.
378, 1247-1257. 1. Signaling by Singlet Oxygen lg Schieke, S. , Klotz, L. , and Sies, H. (1999). Activation pattern of mitogenactivated protein kinases elicited by peroxynitrite: attenuation by selenite supplementation. FEBS Lett. 448, 301-303. , and Baeuerle, P. A. (1992). Nuclear factor KB: An oxidative stressresponsive transcription factor of eukaryotic cells (a review). Free Radical Res. Commun. 17, 221-237. , and Sies, H. (1989). The peroxidase/oxidase activity of soybean lipoxygenase. II.
Rogers, J. , Ulevitch, R. , and Davis, R. J. (1995). Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine. J. Biol. Chem. 270, 7420-7426. , and Karin, M. (1996). Ultraviolet light and osmotic stress: Activation of the JNK cascade through multiple growth factor and cytokine receptors. Science 274, 1194-1197. Rupec, R. , and Baeuerle, P. A. (1995). The genomic response of tumor cells to hypoxia and reoxygenation.
Antioxidant and Redox Regulation of Genes by Chandan K. Sen, Lester Packer, Patrick A. Baeuerle
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