By William D. James MD, Timothy Berger MD, Dirk Elston MD

ISBN-10: 032331967X

ISBN-13: 9780323319676

Effectively diagnose and deal with quite a lot of pores and skin stipulations with the newest variation of the extremely popular Andrews’ ailments of the outside: scientific Dermatology. The twelfth version of this vintage reference, through esteemed authors William D. James, MD, Timothy G. Berger, MD, and Dirk M. Elston, MD, presents state-of-the-art information on newly well-known illnesses, new stipulations, and strange variations of recognized ailments, in addition to new makes use of for tried-and-true drugs and particular medications for ailments as disparate as cancer and rosacea. It’s your perfect go-to resource for scientific dermatology, at each degree of your career.

  • Still the single one-volume, go-to dermatology text!

  • Practice with confidence in the course of the valued authorship of professional pros Dr. William D. James, Dr. Timothy G. Berger, and Dr. Dirk M. Elston.

  • Rapidly enhance your knowledge of pores and skin stipulations via a concise, clinically targeted, basic format.
  • Obtain thorough guidance on medical presentation and treatment for a whole variety of universal and infrequent epidermis ailments.

  • Ensure that you’re up to the mark with the most popular themes in dermatology, including drug eruptions from new medicinal drugs, new therapeutics for cancer, in addition to viral infections, biologic brokers, and newly defined gene pursuits for treatment.
  • NEW! Watch video clips of surgical concepts on-line at
  • Broaden your wisdom with up-to-date info on serological analysis of pemphigus, TNF-I for hidradenitis suppurativa, using immunosuppressives for atopic dermatitis, excimer laser for the remedy of vitiligo and lots more and plenty more.
  • Quickly entry 1000s of latest pictures depicting a large choice of dermis conditions.
  • Stay modern with fresh society guidance, including the newest from the yank Academy of Dermatology, masking a number of stipulations akin to cancer and atopic dermatitis.
  • Expand your scientific repertoire and meet your sufferers’ expectancies with insurance of the latest beauty brokers, their symptoms, and attainable problems.
  • Expert seek advice e-book model incorporated with buy. This more advantageous book event allows you to go looking the entire textual content, figures, and references from the ebook on quite a few devices.

In Andrews’ ailments of the outside, the authors offer working towards dermatologists and citizens with the middle details needed.

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Additional info for Andrews’ Diseases of the Skin: Clinical Dermatology

Sample text

Proc Natl Acad Sci USA 2011; 108(13):5372–5377. A Chilblains (pernio, perniosis) Chilblains constitute a localized erythema and swelling caused by exposure to cold. Blistering and ulcerations may develop in severe cases. In people predisposed by poor peripheral circulation, even moderate exposure to cold may produce chilblain. Cryoglobulins, cryofibrinogens, antiphospholipid antibodies, or cold agglutinins may be present and pathogenic. Chilblain-like lesions may occur in discoid and systemic lupus erythematosus (chilblain lupus), as a presenting sign of leukemia cutis, or if occurring in infancy may herald the NakajoNishimura syndrome.

In childhood, lesions begin as small papules or papulovesicles that crust and become impetiginized. They are intensely pruritic and frequently excoriated. In children, the cheeks, distal nose, ears, and lower lip are typically involved. Cheilitis may be the initial and only feature for years. Conjunctivitis is seen in 10–20% of patients (limbal-type vernal catarrh). Lesions of the arms and legs are also common and usually exhibit a prurigo nodule–like configuration (Fig. 3-23).

Some investigators report that 10–20% of patients with PLE may have positive antinuclear antigens (ANAs) and a family history of lupus erythematosus. Photosensitive systemic lupus erythematosus (SLE) patients may give a history of PLE-like eruptions for years before the diagnosis of SLE is made. PLE patients should be followed for the development of symptoms of SLE. Clinically, the eruption may have several different morphologies, although in the individual patient, the morphology is usually constant.

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Andrews’ Diseases of the Skin: Clinical Dermatology by William D. James MD, Timothy Berger MD, Dirk Elston MD

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