By A. E. Harper, J. K. Tews (auth.), Gerald Huether (eds.)

ISBN-10: 3642731759

ISBN-13: 9783642731754

ISBN-10: 3642731775

ISBN-13: 9783642731778

The photograph at the following web page is being reproduced right here, on the request of the partici­ pants within the complex study Workshop "Amino Acid Availability and mind functionality in healthiness and Disease". I displayed this limewood carving, entitled "Neurochemistry", in the course of my final feedback to this terribly stimulating and efficient workshop so ably prepared by means of my collaborator Dr. Gerald Huether. We scientists want good legs to hold us via the entire twists and turns of our educational careers. we should always even have, because it have been, a reserve leg convenient, to aid us remain upright whilst this profession ends. My "third leg" is wooden carving. the assumption for "Neurochemis­ attempt" got here to me within the aircraft sporting me to the congress of the foreign Neuro­ chemical Society in Jerusalem. we'd like the palms for our meticulous experimental paintings, and at the least one ear to hear the messages our neurons ship us. many years in the past it's going to were untimely to carry a workshop in this topic. Now, in spite of the fact that, the time used to be greatest to permit an summary of the prestige of present re­ seek, and to show the promising new openings it has created. there isn't any doubt that the e-book to be released due to this workshop might be, for the following years a minimum of, the traditional textual content at the topic. Hearty because of all audio system for his or her fantastic con­ tributions and to all individuals for the vigorous, uninhibited and stimulating discussion.

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Additional info for Amino Acid Availability and Brain Function in Health and Disease

Example text

120' 2 3 5 • • • FIGURE 1 Drop of plasma amino acids in newborns after feeding. Each child was given a normal feeding of milk at time zero and blood samples for amino acid analyses were taken at zero, 30, 60, 90 and 120 min. Inverted triangles signify a drop of more than 20 % in the plasma level of the particular amino acids (see text). 17 verted triangle signifies a drop of more than 20 % in the plasma level of the particular non-essential amino acid compared to zero time. The data are incomplete because blood specimens were not obtained for all times for any patients.

FELS, K. (1987). Beeinflussen Tryptophan und Serotonin beim Menschen die Melatonin- AusschOttung und damit die Funktion des "Regulators der Regulatoren" (ZirbeldrOse)? In: Fortschr. , Vol. 3. ). Karger, Basel, pp. 87-99. 2) CAHILL, G. F. , AOKI, 1. , MARLlSS, E. B. (1972). Endocrinology. ), vol. 1, Williams & Wilkins, Baltimore, p. 563. , LI, J. , GOLDBERG, A. L. (1975). Effects of insulin, glucose, and amino acids on protein turnover in rat diaphragm. J. BioI. Chem. 250: 290-298. 4) GOLDBERG, A.

Soc. Exp. Bioi. 32: 65-104. , RAPAPORT, T. A. (1974). A linear steady-state treatment of enzymatic chains. Eur. J. Biochem. 42: 89-95. , KNOWLES, R. , POGSON, C. I. (1986). Quantification of the importance of individual steps in the control of aromatic amino acid metabolism. Biochem. J. 234: 635-647. 21) SMITH, S. , CARR, F. P. , POGSON, C. I. (1980). The metabolism of L-tryptophan by isolated rat liver cells. Biochem. J. 192: 673-686. BIOAVAILABILITY OF AMINO ACIDS AND AMINO ACID PRECURSORS FOR NEUROTRANSMITTER ACTION: THE ROLE OF HORMONES Marie Luise Rao Nervenklinik und Poliklinik, Psychiatrie Rheinische Friedrich-Wilhelms-Universitat Sigmund-Freud-StraBe 25 5300 Bonn 1 Federal Republic of Germany INTRODUCTION In the context of neurotransmitter action, amino acids serve as inhibitory (taurine and glycine) and excitatory neurotransmitters (glutamate and aspartate), precursors of neurotransmitters (tyrosine and tryptophan), and transducers of transmitter components (glycine and serine in transmethylation processes).

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Amino Acid Availability and Brain Function in Health and Disease by A. E. Harper, J. K. Tews (auth.), Gerald Huether (eds.)

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