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Additional resources for Alpha-Lipoic Acid - A Medical Dictionary, Bibliography, and Annotated Research Guide to Internet References
Pyruvic acid). Thioctic acid is pharmacologically active and exhibits antiphlogistic and antinoceceptive (analgetic) as well as cytoprotective properties. An important medical indication is the treatment of diabetic polyneuropathy. g. on account of its antioxidative action. , Biol. Chem. Hoppe-Seyler 373, 333-335, 1992). , Klin. Wochenschr. 1991, 69(15), 722-4) thioctic acid can possibly become significant in the combating of disease caused by HIV-1- and HTLV IIIB viruses. In the case of the pure, optical isomers of thioctic acid (R and S form, that is, R-thioctic acid and S-thioctic acid), in contrast to the racemate the R enantiomer is primarily antiphlogistically and the S enantiomer primarily antinociceptively active (see also EP 0,427,247 A2).
2 theta(Cu) which shifts in the direction of the smaller angular values as the enantiomer content increases. Excerpt(s): Alpha-lipoic acid is used in pharmaceutical formulations both in infusion solutions as well as in solid galenic formulations for oral use. Synthetically produced, racemic DL-alpha-lipoic acid, also designated as RS-thioctic acid, is used for this. An enantiomer of alpha-lipoic acid, R-thioctic acid, occurs as natural substance in practically all animal and vegetable cells. g.
Source: Patrick, L Altern-Med-Revolume 2000 August; 5(4): 290-305 1089-5159 • Pharmacokinetics, tolerability, and fructosamine-lowering effect of a novel, controlled-release formulation of alpha-lipoic acid. Author(s): Northern California Diabetes Institute, Seton Medical Center, Dale City, CA 94015, USA. Source: Evans, Joseph L Heymann, Catherine J Goldfine, Ira D Gavin, Laurence A Endocr-Pract. 2002 Jan-February; 8(1): 29-35 1530-891X 28 Alpha-Lipoic Acid • Prevention of hypertension, insulin resistance, and oxidative stress by alpha-lipoic acid.
Alpha-Lipoic Acid - A Medical Dictionary, Bibliography, and Annotated Research Guide to Internet References by Icon Health Publications, Health Publica Icon Health Publications
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